Determinants of Growth, Adiposity and Bone Mass in Early Life
Year: 2016
Type: dissertation
Study design: Observational Study
Abstract: \n \nEnvironmental influences during fetal life and early infancy have been suggested to influence body composition throughout the life-course. Especially poor fetal nutrition and fetal growth restriction have been designated important risk factors for gaining high fat mass or low bone mass during later life. As body composition tends to track from childhood into adulthood, the fight against widespread overweight and osteoporosis should focus on prevention from early life onwards. This thesis aimed to assess the impact of maternal diet, more specific fish and milk consumption during pregnancy on fetal growth; define the strongest early maternal, paternal, fetal and infant risk factors of preschool overweight, study the influence of maternal smoking on childhood body composition and explore the associations of maternal diet as well as fetal and infant growth patterns with childhood bone mass. To address these aims the studies included in this thesis were conducted within the Generation R Study, a population-based prospective cohort study from fetal life onwards. \n \nThe findings of this thesis indicate maternal fish consumption is not associated with fetal growth characteristics. Maternal she
Author: Denise H. M. Heppe
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2268966863