Work

Memory CD4+ T cells are suppressed by CD8+ regulatory T cells in vitro and in vivo.

Year: 2017

Type: article

Abstract: BACKGROUND: T cells. METHODS: T cells in-vivo, we utilized a murine model of cardiac allograft transplantation. RESULTS: memory T cells, through a Qa-1-peptide-TCR pathway. CONCLUSIONS: memory T cell-mediated acute murine cardiac allograft rejection, and further prolong graft survival times. These results provide new insights into immune regulation of organ rejection.

Source: PubMed

Authors: Xin Long, Qi Cheng, Huifang Liang, Jianping Zhao, Jian Wang, Wei Wang, Stephen Tomlinson, Lin Chen, Carl Atkinson, Bixiang Zhang, Xiaoping Chen, Peng Zhu

Institutions: Tongji Hospital, Huazhong University of Science and Technology, Medical University of South Carolina

Language: English

Topic: T-cell and B-cell Immunology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2583168049

FWCI: 1.307

Cites: 60

Cited by: 19

Related to: 10