A Tale of Two Pathways: Renewing the Promise of Anti-CD40L Blockade
Year: 2017
Type: editorial
Abstract: A new Fc-silent anti-human CD154 domain antibody synergizes with conventional immunosuppressants to control renal transplant rejection in nonhuman primates without evidence of thromboembolism, raising the prospect of its combination with approved costimulation-blocking agents in the clinic. See the article from Kim et al on page 1182.
DOI: 10.1111/ajt.14217
Authors: A.W. Thomson, M.B. Ezzelarab
Institution: University of Pittsburgh
Language: English
Subfield: Transplantation
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,300
OpenAlex ID: W2583331728
