The fate of BRCA1-related germline mutations in triple-negative breast tumors.
Year: 2017
Type: article
Abstract: mutation status prompt for combined germline and tumor genotyping for the classification of TNBC, particularly in the context of clinical trials evaluating synthetic lethality drugs.
Source: PubMed Central
Authors: Vassiliki Kotoula, Florentia Fostira, Kyriaki Papadopoulou, Paraskevi Apostolou, Eleftheria Tsolaki, Georgios Lazaridis, Kyriaki Manoussou, Flora Zagouri, Dimitrios Pectasides, Ioannis Vlachos, Ioannis Tikas, Sotiris Lakis, Irene Konstantopoulou, George Pentheroudakis, Helen Gogas, Pavlos Papakostas, Christos Christodoulou, Dimitrios Bafaloukos, Evangelia Razis, Vasilios Karavasilis, Christina Bamias, Drakoulis Yannoukakos, George Fountzilas
Institutions: Aristotle University of Thessaloniki, National Centre of Scientific Research "Demokritos", Papageorgiou General Hospital, Hellenic Cooperative Oncology Group, National and Kapodistrian University of Athens, Alexandra Hospital, Hippocration General Hospital, University of Thessaly, University Hospital of Ioannina, Laiko General Hospital of Athens, Metropolitan Hospital, Hygeia Hospital
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2584766998