Work

The tug-of-war over MTOR in Legionella infections

Year: 2017

Type: article

Abstract: The tug-of-war over MTOR in Legionella infections – – Previously, we uncovered that mouse bone marrow-derived macrophages (BMMs) infected with pathogenic Legionella suppress MTOR to promote inflammation through a host-driven mechanism. In our recent study (Abshire et al., PLoS Pathogens 2016 Dec 12;12(12):e1006088) we identified the Toll-like Receptor (TLR) adaptor Myeloid differentiation primary response gene 88 (Myd88) as a critical factor mediating the host-induced (...)

Source: Microbial Cell

DOI: 10.15698/mic2017.02.559

Author: Stanimir Ivanov

Institution: Louisiana State University Health Sciences Center Shreveport

Language: English

Topic: Legionella and Acanthamoeba research

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,283