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The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

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Year: 2015
Type: article
Source: Nature
DOI: 10.1038/nature14443
Authors: Colleen A. McHugh, Chun-Kan Chen, Amy Chow, Christine F. Surka, Christina Tran, Patrick McDonel, Amy Pandya-Jones, Mario Blanco, Christina Burghard, Annie Moradian, Michael J. Sweredoski, Alexander A. Shishkin, Julia Su, Eric S. Lander, Sonja Hess, Kathrin Plath, Mitchell Guttman
Institutions: California Institute of Technology, Broad Institute, University of California, Los Angeles, UCLA Jonsson Comprehensive Cancer Center
Language: English

Topic: Cancer-related molecular mechanisms research
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Center for Research Resources
Awards: G1076877717, PREDOCTORAL TRAINING IN BIOLOGY AND CHEMISTRY, G2611446826, Mechanism of chromatin remodeling and gene silencing by the lncRNAs Xist and Tsix, Deciphering the mechanism of large ncRNA mediated regulation of cell state, CHROMATIN AND EPIGENETIC INHERITANCE
OpenAlex ID: W2032640007
FWCI: 45.05
Cites: 45
Cited by: 1,163
Related to: 10
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