Work

Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL‐10 expression and secretion

Year: 2017

Type: article

Abstract: gene expression and enhances IL-10 protein secretion. The demonstration that EV-YF1 confers cardioprotection highlights the potential importance of diverse exosomal contents of unknown function, above and beyond the usual suspects (e.g., microRNAs and proteins).

Source: EMBO Molecular Medicine

DOI: 10.15252/emmm.201606924

Authors: Linda Cambier, Geoffrey de Couto, Ahmed Ibrahim, Antonio K Echavez, Jackelyn Valle, Weixin Liu, Michelle Kreke, Rachel R Smith, Linda Marbán, Eduardo Marbán

Institutions: Cedars-Sinai Medical Center, Cedars-Sinai Smidt Heart Institute

Language: English

Topic: Extracellular vesicles in disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $7,990

Funders: California Institute for Regenerative Medicine, National Institutes of Health, Centers for Disease Control and Prevention, National Heart, Lung, and Blood Institute

Awards: Exosome-based therapeutics for heart failure, G8151559239

OpenAlex ID: W2587206126

FWCI: 10.72

Cites: 72

Cited by: 227

Related to: 10