Work

Langerhans-Cell Histiocytosis

Year: 2018

Type: article

Abstract: A spectrum of diseases formerly known as histiocytosis X and now called Langerhans-cell histiocytosis is characterized by ERK pathway activation (including BRAF V600E mutations) and diverse clinical manifestations involving bone, skin, lung, and pituitary.

Source: New England Journal of Medicine

DOI: 10.1056/nejmra1607548

Authors: Carl E. Allen, Miriam Merad, Kenneth L. McClain

Institutions: Baylor College of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai

Language: English

Topic: Histiocytic Disorders and Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute