Work

Cholecystokinin-2/gastrin antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anti-inflammatory analgesics for the treatment of inflammatory bowel disease

Year: 2017

Type: article

Abstract: Arylated 5-hydroxy-pyrrol-2-ones were prepared in 2 synthetic steps from mucochloric acid and optimised as CCK 2 -selective ligands using a range of assays.

Source: MedChemComm

DOI: 10.1039/c6md00707d

Authors: E. Lattmann, J. Sattayasai, R. Narayanan, N. Ngoc, D. Burrell, P. N. Balaram, T. Palizdar, P. Lattmann

Institutions: Aston University, Khon Kaen University, University of Tennessee Health Science Center

Language: English

Topic: Synthesis and Characterization of Pyrroles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2587879392

FWCI: 0.664

Cites: 29

Cited by: 13

Related to: 10