Impaired Cognitive Flexibility and Intact Cognitive Control in Autism: A Computational Cognitive Neuroscience Approach
Year: 2005
Type: article
Abstract: In people with autism, the ability to enact a behavior in the presence of competing responses appears intact, while the ability to fluently adapt cognitive control in the face of changing task contingencies is impaired.In this paper, the Cross-Task Generalization model (Rougier et al., 2005), which offers a formal account of the effect of dopamine on frontal cortex function, is used to capture performance of both normally functioning individuals and people with autism on a classic test of cognitive control, the Stroop task (Stroop, 1935), and one of cognitive flexibility, the Wisconsin Card Sort Test (Berg, 1948).By weakening the effect of the dopamine's signal on frontal cortex, the model fits quantitative and qualitative results of autistic performance on these tasks and demonstrates the potential usefulness of this approach in autism research.
Author: John Kulvicki
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
Funder: Vanderbilt University
OpenAlex ID: W2588701856