Work

Cultured Cells Isolated from CNS Indolent B-Cell Lymphoma Have Characteristics of Mesenchymal Stem Cells: A Clinical Case and Scientific Research.

Year: 2018

Type: article

Abstract: in medium containing 10% fetal bovine serum (FBS) and characterized by their morphology, growth, phenotype, clonogenicity and osteogenic differentiation. It was apparent that the cultured cells isolated from the indolent B- cell lymphoma located in the CNS have the basic characteristics of mesenchymal stem cells. The presence of MSCs is described for the very first time in such type of tumor. The well-known immunosuppressive properties of the MSCs may represent another mechanism favouring the tumor growth.

Source: PubMed Central

Authors: Kalina Tumagelova-Yuzeir, Ekaterina Ivanova-Todorova, Emanuil Naydenov, Tsvetelina Velikova, Ekaterina Krasimirova, Kalina Belemezova, Tihomir Dikov, Marin Penkov, Sevdalin Nachev, Margarita Genova, Dobroslav Kyurkchiev

Institutions: Medical University of Sofia, University Hospital St. Ivan Rilski, National Specialized Hospital for Active Treatment of Hematologic Diseases

Language: English

Topic: Mesenchymal stem cell research

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2589308187

FWCI:

Cites: 14

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Related to: 10