Work

Patterns of DNMT1 Promoter Methylation in Patients with Acute Lymphoblastic Leukemia.

Year: 2017

Type: article

Abstract: Analysis of promoter methylation patterns in various subgroups of ALL has revealed the importance of DNMT1 in the regulation of gene expression. Likewise, extensive data have also highlighted the methylation-based mechanisms exerted by DNAM1 as one of the main participants regulating gene expression in B-ALL and T-ALL patients. Investigation of the overall DNA methylation pattern offers significant improvements in the prediction of disease prognosis and treatment response.

Source: PubMed Central

Authors: Tirdad Rahmani, Mehdi Azad, Bahram Chahardouli, Hajar Nasiri, Mousa Vatanmakanian, Saeid Kaviani

Institutions: Tarbiat Modares University, Qazvin University of Medical Sciences, Tehran University of Medical Sciences, Children's Medical Center

Language: English

Topic: Acute Lymphoblastic Leukemia research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2590516380

FWCI: 2.685

Cites: 25

Cited by: 28

Related to: 10