Work

Hydrogen-rich water protects against inﬂammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression

Year: 2017

Type: article

Abstract: AIM: To investigate the therapeutic effect of hydrogen-rich water (HRW) on inﬂammatory bowel disease (IBD) and to explore the potential mechanisms involved. METHODS: d after IBD modeling to determine clinical symptoms, colonic inﬂammation and the potential mechanisms involved. RESULTS: < 0.05). The histological study also showed more serious colonic damage that was similar to the DSS group. CONCLUSION: HRW has a significant therapeutic potential in IBD by inhibiting inflammatory factors, oxidative stress and ER stress and by up-regulating HO-1 expression.

Source: World Journal of Gastroenterology

DOI: 10.3748/wjg.v23.i8.1375