Handheld spatial frequency domain spectrographic imager for depth-sensitive, quantitative spectroscopy of skin tissue
Year: 2017
Type: conference-paper
Abstract: Here we present a handheld, implementation of Spatial Frequency Domain Spectroscopy (SFDS) that employs line imaging. The new instrument can measure 1088 spatial locations that span a 3 cm line as opposed to our benchtop system that only collects a single 1 mm diameter spot. This imager, however, retains the spectral resolution (~ 1 nm) and range (450 to 1000 nm) of our benchtop system. The device also has tremendously improved mobility and portability, allowing for greater ease of use in clinical setting. A smaller size also enables access to different tissue locations, which increases the flexibility of the device. The design of this portable system not only enables SFDS to be used in clinical settings, but also enables visualization of properties of layered tissues such as skin.
DOI: 10.1117/12.2252518
Institution: Beckman Laser Institute and Medical Clinic
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: Arnold and Mabel Beckman Foundation, Institute of Clinical and Translational Sciences, National Institutes of Health, U.S. Air Force, National Institute of Biomedical Imaging and Bioengineering, Institute for Clinical and Translational Science, University of California, Irvine, Air Force Office of Scientific Research
Award: G7861206232
OpenAlex ID: W2590997161
