Work

The Impact of Pre- and Week 4 Post-Transplant CMV-Specific Elispot Assay on CMV Reactivation and Survival in CMV-Seropositive Allogeneic Hematopoietic Cell Transplant (Allo-HCT) Recipients

Year: 2017

Type: article

Abstract: Background: CMV infection causes significant morbidity and mortality in allo-HCT. CMV cell-mediated immunity (CMI), assessed by engrafted T cell production of IFN-γ, is a major mechanism to control CMV replication. The potential role of pre- and post-transplant CMI and its impact on CMV replication and survival is not well understood.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2016.12.010

Authors: Ella J. Ariza-Heredia, Dimpy P. Shah, Drew J. Winston, Scott D. Rowley, Kathleen M. Mullane, Pranatharthi Chandrasekar, Parameswaran Hari, Robin K. Avery, Karl S. Peggs, Deepali Kumar, Rajneesh Nath, Per T. Ljungman, Sherif B. Mossad, Sanjeet S. Dadwal, William Cruikshank, Roy F. Chemaly

Institutions: The University of Texas MD Anderson Cancer Center, University of California, Los Angeles, Los Angeles Medical Center, Hackensack University Medical Center, University of Chicago Medical Center, Wayne State University, The Barbara Ann Karmanos Cancer Institute, Medical College of Wisconsin, Johns Hopkins University, University College London, Toronto General Hospital, University of Massachusetts Chan Medical School, Karolinska University Hospital, Cleveland Clinic, City Of Hope National Medical Center, City of Hope, Oxford Immunotec (United Kingdom)

Language: English

Topic: Cytomegalovirus and herpesvirus research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650

OpenAlex ID: W2591099348

FWCI:

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