Work

Transcriptional activation of lipogenesis by insulin requires phosphorylation of MED17 by CK2

Year: 2017

Type: article

Abstract: Phosphorylation of MED17 by distinct kinases enables nutrient-dependent transcriptional activation of lipogenesis by insulin.

Source: Science Signaling

DOI: 10.1126/scisignal.aai8596

Authors: Jose A. Viscarra, Yuhui Wang, Il-Hwa Hong, Hei Sook Sul

Institution: University of California, Berkeley

Language: English

Topic: Lipid metabolism and biosynthesis

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Research Resources

Awards: G1637196319, G3033304897, The Role of the Mediator Complex in the Transcriptional Regulation of Lipogenesis, G5128153250, Regulation of Lipogenesis, G7965749062, LTQ XL Linear Quadrupole Ion Trap Mass Spectrometer

OpenAlex ID: W2591349052

FWCI: 1.661

Cites: 33

Cited by: 29

Related to: 10