Treatment of CNS-Restricted Familial Hemophagocytic Lymphohistiocytosis with Allogeneic Hematopoietic Cell Transplantation
Year: 2017
Type: article
Abstract: Familial hemophagocytic lymphohistiocytosis (FHL) is a lethal inherited disorder resulting in primary hemophagocytic lymphohistiocytosis (HLH). Allogeneic hematopoietic cell transplantation (HCT) is curative therapy for FHL. Central nervous system (CNS) manifestations are common in systemic HLH, but it is incompletely characterized if CNS-restricted cases of HLH can occur in the absence of systemic HLH findings, and whether CNS-restricted HLH responds to HCT.
Authors: Hojun Li, Leslie Benson, Lauren Henderson, Alyssa Kennedy, Leslie Lehmann, Michelle Lee, Barbara Degar, Mark Gorman, Christine Duncan
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2591501670