Challenges with Diagnosing Pulmonary Chronic GVHD in Children as Per the 2014 National Institutes of Health Consensus Criteria: Applied Biomarkers of Late Effects (ABLE)/Pediatric Blood and Marrow Transplant Consortium (PBMTC) 1202 Study
Year: 2017
Type: article
Abstract: Introduction: The 2014 National Institutes of Health consensus criteria (NIH-CC) allows pulmonary cGVHD to be diagnosed based upon the combination of obstructive lung defects on pulmonary function testing (PFTs), CT findings (bronchiectasis, air trapping), and absence of infection (collectively termed bronchiolitis obliterans syndrome), rather than requiring biopsy-proven bronchiolitis obliterans (BO). We sought to understand the reliability of the 2014 NIH-CC for diagnosing pulmonary cGVHD in children within the context of a multi-institutional study.
Authors: Geoff D.E. Cuvelier, Eneida R. Nemecek, Justin T. Wahlstrom, Andrew C. Harris, Michael A. Pulsipher, Victor Lewis, Henrique Bittencourt, Sung Won Choi, Carrie L. Kitko, Emi Caywood, Monica Bhatia, Kimberly A. Kasow, David A. Jacobsohn, Aleksandra Petrovic, Albert Kerhadpour, Sonali Chaudhury, Joseph H. Chewning, Tal Schechter, Cori Abikoff, Don W. Coulter, Michael Joyce, Sureyya Savasan, Anna Pawlowska, Gail Megason, David Mitchell, Alexandra Cheerva, Anat Halevy, Kirk R. Schultz
Institutions: CancerCare Manitoba, Oregon Health & Science University, Doernbecher Children's Hospital, University of California, San Francisco, UCSF Benioff Children's Hospital, Primary Children's Hospital, University of Utah, Children's Hospital of Los Angeles, Alberta Children's Hospital, Centre Hospitalier Universitaire Sainte-Justine, University of Michigan, Vanderbilt University Medical Center, Alfred I. duPont Hospital for Children, Columbia University Irving Medical Center, Columbia University, University of North Carolina at Chapel Hill, Children's National, Johns Hopkins All Children's Hospital, Loma Linda University Medical Center, Northwestern University, Lurie Children's Hospital, University of Alabama at Birmingham, Hospital for Sick Children, New York Medical College, University of Nebraska Medical Center, Nemours Children's Clinic, Children's Hospital of Michigan, City Of Hope National Medical Center, City of Hope, University of Mississippi Medical Center, Montreal Children's Hospital, McGill University Health Centre, University of Louisville, University of British Columbia, Child and Family Research Institute, BC Children's Hospital
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2591507159