Work

Cerenkov luminescence imaging: physics principles and potential applications in biomedical sciences

Year: 2017

Type: article

Abstract: Cerenkov luminescence imaging (CLI) is a novel imaging modality to study charged particles with optical methods by detecting the Cerenkov luminescence produced in tissue. This paper first describes the physical processes that govern the production and transport in tissue of Cerenkov luminescence. The detectors used for CLI and their most relevant specifications to optimize the acquisition of the Cerenkov signal are then presented, and CLI is compared with the other optical imaging modalities sharing the same data acquisition and processing methods. Finally, the scientific work related to CLI and the applications for which CLI has been proposed are reviewed. The paper ends with some considerations about further perspectives for this novel imaging modality.

Source: EJNMMI Physics

DOI: 10.1186/s40658-017-0181-8

Authors: Esther Ciarrocchi, Nicola Belcari

Institutions: University of Pisa, Istituto Nazionale di Fisica Nucleare, Sezione di Pisa, Istituto Nazionale di Fisica Nucleare

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $2,490

OpenAlex ID: W2592190155

FWCI: 8.713

Cites: 146

Cited by: 122

Related to: 10