Work

Prognostic significance of β2-adrenergic receptor expression in non-small cell lung cancer.

Year: 2016

Type: article

Abstract: BACKGROUND: The β2-Adrenergic receptor (β2-AR) is associated with tumor growth and progression. However, the clinical significance of β2-AR expression in patients with non-small cell lung cancer (NSCLC) remains unclear. METHODS: Three hundred twenty-eight patients with surgically resected NSCLC were retrospectively investigated. Tumor sections were stained by immunohistochemistry for assessing β2-AR and Ki-67 expression and microvessel density (MVD), which was using CD34 levels. RESULTS: =0.031). CONCLUSION: β2-AR expression is an independent prognostic factor for early-stage AC patients.

Source: PubMed Central

Authors: Tomohiro Yazawa, Kyoichi Kaira, Kimihiro Shimizu, Akira Shimizu, Keita Mori, Toshiteru Nagashima, Yoichi Ohtaki, Tetsunari Oyama, Akira Mogi, Hiroyuki Kuwano

Institutions: Gunma University, Gunma University Hospital, Shizuoka Cancer Center

Language: English

Topic: Cancer, Stress, Anesthesia, and Immune Response

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2593644105

FWCI: 0.941

Cites: 44

Cited by: 29

Related to: 10