Work

Exhaustive Suzuki–Miyaura reactions of polyhalogenated heteroarenes with alkyl boronic pinacol esters

Year: 2017

Type: article

Abstract: A novel Suzuki-Miyaura protocol is described that enables the exhaustive alkylation of polychlorinated pyridines. This method facilitates a formal synthesis of normuscopyridine and the rapid assembly of a dumbbell shaped portion of a [2]rotaxane.

Source: Chemical Communications

DOI: 10.1039/c7cc00997f

Authors: Sébastien Laulhé, J. Miles Blackburn, Jennifer L. Roizen

Institutions: Indiana University Indianapolis, Indiana University – Purdue University Indianapolis, Duke University

Language: English

Topic: Catalytic Cross-Coupling Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Science Foundation, American Chemical Society Petroleum Research Fund, National Institute of General Medical Sciences

Awards: Pharmacological Sciences Training Grant, MRI: Acquisition of a TOF High Resolution Mass Spectrometer, G5833396658