Advancing Diagnostics to Address Antibacterial Resistance: The Diagnostics and Devices Committee of the Antibacterial Resistance Leadership Group
Year: 2016
Type: article
Abstract: Diagnostics are a cornerstone of the practice of infectious diseases. However, various limitations frequently lead to unmet clinical needs. In most other domains, diagnostics focus on narrowly defined questions, provide readily interpretable answers, and use true gold standards for development. In contrast, infectious diseases diagnostics must contend with scores of potential pathogens, dozens of clinical syndromes, emerging pathogens, rapid evolution of existing pathogens and their associated resistance mechanisms, and the absence of gold standards in many situations. In spite of these challenges, the importance and value of diagnostics cannot be underestimated. Therefore, the Antibacterial Resistance Leadership Group has identified diagnostics as 1 of 4 major areas of emphasis. Herein, we provide an overview of that development, highlighting several examples where innovation in study design, content, and execution is advancing the field of infectious diseases diagnostics.
Source: Clinical Infectious Diseases
DOI: 10.1093/cid/ciw831
Authors: Ephraim L. Tsalik, Elizabeth Petzold, Barry N. Kreiswirth, Robert A. Bonomo, Ritu Banerjee, Ebbing Lautenbach, Scott R. Evans, Kimberly E. Hanson, Jeffrey D. Klausner, Robin Patel, of the Antibacterial Resistance Leadership Group
Institutions: Duke Medical Center, Durham VA Medical Center, Rutgers, The State University of New Jersey, Rutgers New Jersey Medical School, Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, Vanderbilt University, University of Pennsylvania, Harvard University, University of Utah, University of California, Los Angeles, Mayo Clinic
Language: English
Subfield: Clinical Biochemistry
Domain: Life Sciences
Open Access status: green
Award: G1801780589
OpenAlex ID: W2594014684