Work

General and Efficient C–C Bond Forming Photoredox Catalysis with Semiconductor Quantum Dots

Year: 2017

Type: article

Abstract: Photoredox catalysis has become an essential tool in organic synthesis because it enables new routes to important molecules. However, the best available molecular catalysts suffer from high catalyst loadings and rely on precious metals. Here we show that colloidal nanocrystal quantum dots (QDs) can serve as efficient and robust, precious-metal free, photoassisted redox catalysts. A single-sized CdSe quantum dot (3.0 ± 0.2 nm) can replace several different dye catalysts needed for five different photoredox reactions (β-alkylation, β-aminoalkylation, dehalogenation, amine arylation, and decarboxylative radical formation). Even without optimization of the QDs or the reaction conditions, efficiencies rivaling those of the best available metal dyes were obtained.

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.6b13379

Authors: Jill A. Caputo, Leah C. Frenette, Norman Zhao, Kelly L. Sowers, Todd D. Krauss, Daniel J. Weix

Institution: University of Rochester

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500