Protein Intake and Mobility Limitation in Community‐Dwelling Older Adults: the Health ABC Study
Year: 2017
Type: article
Study design: Observational Study
Abstract: OBJECTIVES: The current Recommended Dietary Allowance (RDA) for protein is based on short-term nitrogen balance studies in young adults and may underestimate the amount needed to optimally preserve physical function in older adults. We examined the association between protein intake and the onset of mobility limitation over 6 years of follow-up in older adults in the Health ABC study. DESIGN: Prospective cohort study. SETTING: Memphis, Tennessee and Pittsburgh, Pennsylvania. PARTICIPANTS: Community-dwelling, initially well-functioning adults aged 70-79 years (n = 1998). MEASUREMENTS: Protein intake (g/kg body weight/d) was calculated using an interviewer-administered 108-item food frequency questionnaire at baseline. Mobility limitation was assessed semi-annually and defined as reporting any difficulty walking one-quarter of a mile or climbing 10 steps on 2 consecutive 6-month contacts. The association between protein intake and incident mobility limitation was examined using Cox proportional hazard regression models adjusting for demographics, behavioral characteristics, chronic conditions, total energy intake, and height. RESULTS: Mean (SD) protein intake was 0.91 (0.38) g/kg body weight/d, with 43% reporting intakes less than the RDA (0.8 g/kg body weight/d). During 6 years of follow-up, 705 participants (35.3%) developed mobility limitations. Compared to participants in the upper tertile of protein intake (≥1.0 g/kg body weight/d), participants in the lower two tertiles of protein intake (<0.7 and 0.7 -<1.0 g/kg body weight/d) were at greater risk of developing mobility limitation over 6 years of follow-up (RR (95% CI): 1.86 (1.41-2.44) and 1.49 (1.20-1.84), respectively). CONCLUSION: Lower protein intake was associated with increased risk of mobility limitation in community-dwelling, initially well-functioning older adults. These results suggest that protein intakes of ≥1.0 g/kg body weight/d may be optimal for maintaining physical function in older adults.
DOI: 10.1111/jgs.14856
Authors: Denise K. Houston, Janet A. Tooze, Katelyn Garcia, Marjolein Visser, Susan Rubin, Tamara B. Harris, Anne B. Newman, Stephen B. Kritchevsky, the Health ABC Study
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Awards: G100949702, G1083180012, G1098417741, Peripheral nerve decline: an underappreciated cause of injurious falls, Dietary protein and change in physical function in black and white older adults, G2245013492, G2563212446, G2638957688, G2815873878, G3570525151, PRevention Of Malnutrition In Senior Subjects in the EU, G5612504302, G581554933, End of Life in the Very Old, G670738241, G861947890, Pittsburgh Older Americans Independence Center, Wake Forest Claude D. Pepper OAIC - Renewal
OpenAlex ID: W2595646555