Year: 2011
Type: article
Abstract: Objective: The purpose of this study was to quantify bone damage associated with insertion of miniscrew implants (MSIs) and relate the amount of bone damage to monocortical plate thickness.Methods: Non-drilling (n=28), self-drilling (n=28) MSI (6X1.6mm,Dentaurum, Newtown, PA) and pilot holes (n=26) were placed bilaterally in the maxilla and mandible of five adult dogs immediately after sacrifice.Bone blocks were cut, bulk stained with 1% basic fuchsin, embedded in methyl methacrylate, sectioned, and mounted.Monocortical plate thickness was measured on both the coronal and basal sides of the insertion site using a calibrated computer program (MicroSuite, Olympus, Tokyo, Japan).Total fractional damaged area (%), fractional microdamaged area (%), and fractional diffuse damaged area (%) were quantified for each specimen using standard histomorphometric methods.Damage was quantified at distances of 0-0.5mm (adjacent region) and 0.5-1mm (distant region) from the bone-implant interface.Results: Monocortical plate thickness of specimens from the mandible was significantly (p<0.001)greater than specimens from the maxilla (2.2 mm and 0.9 mm, respectively).The three damage parameters were greater with self-drilling MSIs than non-drilling MSIs in the mandible, but there were no differences in the maxilla.Fractional microdamaged area associated with both MSIs was greater in the mandible than in the maxilla.Conclusions: SD MSIs are associated with greater bone damage than ND MSIs in bone iii with monocortical thickness of 2.2 mm, but there is no difference in damage between SD and ND MSIs in bone with monocortical thickness of 0.9 mm.Bone damage associated with MSI insertion is greater in bone of 2.2 mm monocortical thickness than 0.9 mm thickness for both self-drilling and non-drilling MSIs.iv Dedicated to my husband Dr. Kyle Shank and my parents Rex and Cheri Crane v ACKNOWLEDGEMENTS I am grateful to the members of my committee for their guidance, support, and patience during the course of this study.I would like to thank Dr. Huja, my advisor, for the many hours he spent teaching me about histomorphometry, miniscrew implants, bone biology, and the research process.I thank Dr. Beck for his willingness to perform statistical analysis multiple times and to help me think critically about the study design.He has been a constant encouragement along the way.I appreciate Dr. Litsky's willingness to serve as an external member of my thesis committee, and I value his insight and experience.I would like to thank the support staff of Dr. Huja's lab.Andrew D'Atri was instrumental in the preparation of specimens.Sarah Hueni and Hina Khurana were involved in the blinding of the specimens for quantification.Delta Dental provided the funding for this project, along with additional support from Dr. Sarandeep Huja's laboratory at the Ohio State University College of Dentistry.Dentaurum donated the miniscrew implants used in the study.Finally, I would like to thank my husband and my family for their love, support, and encouragement during these busy years.Without their help, none of this would have been possible.
Author: Stephanie Brooke Shank
Institution: The Ohio State University
Language: English
Subfield: Orthodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2596112972