A Closer Look at the Diagnostic Utility of Phonemic Paraphasic Errors in Conjunction with the Postictal Language Delay
Year: 2006
Type: article
Abstract: Past research suggests that language disturbances occurring immediately after (postictal) or between (interictal) seizures can accurately predict language dominant (DOM) seizure focus (Privitera, Morris & Gilliam, 1991;Fargo, Schefft, Dulay, Privitera & Yeh, 2005;Schefft, Testa, Dulay, Privitera & Yeh, 2003).The current study conducted a comprehensive investigation of the diagnostic utility of three expressive language disturbances in lateralizing DOM temporal lobe epilepsy (TLE): the postictal language delay (PILD), the time taken to correctly read a test phrase out loud immediately following seizures, and the production of postictal and interictal phonemic paraphasic errors (PPPE and IPPE, respectively).This was accomplished using logistic regression, area under the ROC curve analyses and sensitivity, specificity, positive predictive value and negative predictive values were also computed.Results suggest that PILD, PPPE and IPPE production have very high diagnostic accuracy in lateralizing seizure focus to the DOM hemisphere.project to its end.I would also like to thank Steven Howe, Ph.D. for his indispensable contributions and critical involvement in the data analysis and editing processes.Additionally, I would like to thank Michael Privitera, M.D. for his encouragement and valuable insights through the data collection/management and writing processes.I would also like to
Author: Maya J. Ramirez
Institution: University of Cincinnati
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Epilepsy Foundation
OpenAlex ID: W2596339309