Year: 2006
Type: article
Abstract: Activation of the stress response by a period of restraint stress induces cognitive alterations in humans and animals.Either cognitive enhancements or deficits can result after restraint stress.The reason for the inconsistencies in the stress literature may be due to the variety of restraint lengths and intensities used.Therefore, the aims of our study were to 1.) determine if thirty minutes of restraint stress enhanced or decreased performance on a passive avoidance task, 2.) rule out pain sensitivity alterations that may have contributed to performance changes, and 3.) to examine time-dependent and reinstatement measures with restraint stress.In order to examine the effect of acute restraint stress on learning of a passive avoidance task in male Long-Evans rats, 30 minutes of restraint was administered either immediately prior to training or after training in Experiment 1. Thirty minutes of restraint stress decreased performance at test in stressed rats if restraint was administered immediately prior to training, but did not affect the animal's performance if the stressor was administered immediately after training.Experiment 2 replicated the deficit in performance found in Experiment 1, and determined that the effect of restraint stress was short-lived.If 30 minutes of restraint was
Author: Kathryn J. Bryan
Institution: Kent State University
Language: English
Subfield: Behavioral Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2597398069