Imaging small animal whole-body dynamics by single-impulse panoramic photoacoustic computed tomography
Year: 2017
Type: conference-paper
Abstract: Imaging of small animals, especially rodents provides physiological, pathological, and phenotypical insights into the most relevant milieu—an intact, living system. Currently, non-optical small-animal wholebody imaging approaches lack either spatiotemporal resolution or functional contrasts, whereas pure optical imaging suffers from either shallow penetration (up to ~1 mm) or a poor resolution-to-depth ratio (~1/3). Here, we present a standalone system that breaks all the above limitations. Our system features high spatiotemporal resolution and deep penetration, and can capture anatomical and functional contrasts. We imaged mouse wholebody dynamics in real time with clear sub-organ anatomical and functional details.
DOI: 10.1117/12.2251593
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: bronze
Awards: Photon tunneling: Shedding new light on biomedicine, WHOLE-BODY SMALL-ANIMAL PHOTOACOUSTIC-ULTRASONIC COMPUTED TOMOGRAPHY, Fast high-resolution deep photoacoustic tomography of action potentials in brains, In vivo imaging of single circulating cells, HIGH-FREQUENCY ULTRASONIC AND PHOTOACOUSTIC IMAGING SYSTEM
OpenAlex ID: W2602439357