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A first-in-human phase Ib study to evaluate the MEK inhibitor GDC-0973, combined with the pan-PI3K inhibitor GDC-0941, in patients with advanced solid tumors.

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Year: 2012
Type: conference-abstract
Source: Journal of Clinical Oncology
DOI: 10.1200/jco.2012.30.15_suppl.2566
Authors: Patricia LoRusso, Geoffrey Shapiro, Shuchi Sumant Pandya, Eunice Lee Kwak, Cheryl Jones, Marcia Belvin, Luna C. Musib, Alex de Crespigny, Meghan McKenzie, Mary R. Gates, Iris Tan-Chi Chan, Johanna C. Bendell
Institutions: The Barbara Ann Karmanos Cancer Institute, Dana-Farber Cancer Institute, Beth Israel Deaconess Medical Center, Harvard University, Massachusetts General Hospital, Genentech, Sarah Cannon
Language: English

Topic: Melanoma and MAPK Pathways
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W2602871482
Cites:
Cited by: 48
Related to: 10
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