Work

Mutant BRAF upregulates MCL-1 to confer apoptosis resistance that is reversed by MCL-1 antagonism and cobimetinib in colorectal cancer.

Year: 2017

Type: conference-abstract

Source: Journal of Clinical Oncology

DOI: 10.1200/jco.2017.35.4_suppl.603

Authors: Hisato Kawakami, Shengbing Huang, Krishnendu Pal, Debabrata Mukhopadhyay, Frank A. Sinicrope

Institutions: Mayo Clinic, Mayo Clinic in Florida

Language: English

Topic: Melanoma and MAPK Pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2603163983

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