Successful treatment of Rosai–Dorfman disease using in situ photoimmunotherapy
Year: 2017
Type: article
Study design: Case Report
Abstract: Rosai-Dorfman disease is difficult to cure. In situ photoimmunotherapy combines local photothermal therapy with immunoadjuvant. In the present case report, a 39-year-old Chinese man with Rosai-Dorfman disease lesions below the left nostril and left preauricular region was treated with in situ photoimmunotherapy. The patient was treated with daily application of topical imiquimod (5%) and laser irradiations every 2 weeks for 8 weeks. After three cycles of treatment, the lesions improved markedly without adverse effects. Our results showed that in situ photoimmunotherapy can be used as an effective treatment for Rosai-Dorfman disease.
Authors: WeiR Chen, Xiuli Wang, Meng Li, Lei Shi, Min Luo, Jia Chen, Bo Wang, Fuhe Zhang, Uma Keyal, AnilKumar Bhatta
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2603466064