Work

Design, synthesis, and X-ray structural studies of BACE-1 inhibitors containing substituted 2-oxopiperazines as P1′-P2′ ligands

Year: 2017

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2017.04.011

Authors: Arun K. Ghosh, Margherita Brindisi, Yu-Chen Yen, Emilio L. Cárdenas, Jean-Rene Ella-Menye, Nagaswamy Kumaragurubaran, Xiangping Huang, Jordan Tang, Andrew D. Mesecar

Institutions: Purdue University West Lafayette, Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, University of Oklahoma

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, Office of Science, Office of the Executive Vice President for Research and Partnerships, Purdue University, National Cancer Institute, National Institute of General Medical Sciences, Argonne National Laboratory

Awards: G107546177, Cancer Center Support Grant, DESIGN AND SYNTHESIS OF NONPEPTIDE PROTEASE INHIBITORS, Design & Synthesis of Nonpeptide Protease Inhibitors

OpenAlex ID: W2604182201

FWCI: 1.819

Cites: 40

Cited by: 20

Related to: 10