Pd51-02 Identifying the Optimal Candidate for Early Salvage Radiation Therapy After Radical Prostatectomy for Prostate Cancer: a Long-term Multi-institutional Analysis
Year: 2017
Type: article
Study design: Observational Study
Abstract: METHODS: Patients throughout the US with self-described complications of vaginal mesh were recruited through advertisements to complete an internet-based anonymous survey.All patients filled out the PCS and the Genitourinary Pain Index (GUPI) questionnaire.The PCS is a 13-question survey with scores ranging from 0-52.Previous studies have established distribution of scores from subjects with chronic pain, with a score of 30 or higher representing the highest quartile, thus a score 30 was used to define high pain catastrophizing.Additional data was abstracted including age, number of previous pelvic surgeries, and intent to sue.Statistical analysis was performed using c 2 test and t-test for categorical and continuous variables, respectively.RESULTS: A total of 133 patients were included in the study, of which 78 patients (59%) were found to have high pain catastrophizing.There was no significant difference between baseline age, intent to sue, or number of previous pelvic surgeries between those who catastrophized and did not.Patients who catastrophized were significantly more likely to have a higher GUPI score (33.8 vs. 27.7,p<0.001) along with significant differences in pain (16.3 vs. 13.0,p<0.001) and quality of life (10.8 vs. 9.1, p<0.001) subdomains.Furthermore, patients who catastrophized tended to have less hope that they would recover (38.5% vs. 23.6%)which approached but did not reach statistical significance (p¼0.072).CONCLUSIONS: Patients with self-described mesh complications have a high rate of pain catastrophizing, which is associated with significantly worse quality of life and pain scores.Given that previous studies have also shown catastrophizing is associated with higher pain intensity, disability, and psychological distress (Weber et al, 2001), identifying high catastrophizing patients in the setting of chronic pelvic pain from mesh complications may help guide treatment and be an indicator for early or adjunctive psychosocial intervention.
Source: The Journal of Urology
Authors: Nicola Fossati, R. Jeffrey Karnes, Stephen Boorjian, Michele Colicchia, Alberto Bossi, Thomas Seisen, Cesare Cozzarini, Claudio Fiorino, Barbara Noris Chiorda, Giorgio Gandaglia, Thomas Wiegel, Shahrokh F. Shariat, Gregor Goldner, Steven Joniau, Antonino Battaglia, Karin Haustermans, Gert De Meerleer, Valérie Fonteyne, Piet Ost, Hein Van Poppel, Francesco Montorsi, Alberto Briganti
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2604713502