Work

A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia

Year: 2017

Type: article

Source: Cell stem cell

DOI: 10.1016/j.stem.2017.01.011

Authors: Max A. Cayo, Sunil K. Mallanna, Francesca Di Furio, Ran Jing, Lauren B. Tolliver, Matthew Bures, Amanda Urick, Fallon K. Noto, Evanthia E. Pashos, Matthew D. Greseth, Maciej Czarnecki, Paula Traktman, Wenli Yang, Edward E. Morrisey, Markus Grompe, Daniel J. Rader, Stephen A. Duncan

Institutions: Medical College of Wisconsin, Medical University of South Carolina, University of Pennsylvania, MUSC Hollings Cancer Center, Oregon Health & Science University

Language: English

Topic: Pluripotent Stem Cells Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: W. M. Keck Foundation, Medical College of Wisconsin, National Institutes of Health, National Human Genome Research Institute, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Advancing Translational Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G152989940, iPS-derived hepatocytes for interrogation of lipid phenotypes, G4559400560, Transcriptional Regulation of Mammalian Hepatic Development, Molecular Basis of Human Hepatic Progenitor Cell Formation, Clinical and Translational Science Award, G8068924434, Modeling liver metabolism with patient-specific iPS derived hepatocytes, G9000017913, G9000271108, Medical University of South Carolina - Cancer Center Support Grant

OpenAlex ID: W2604802828

FWCI: 6.93

Cites: 78

Cited by: 116

Related to: 10