Work

Identification of novel 2-(benzo[ d ]isoxazol-3-yl)-2-oxo- N -phenylacetohydrazonoyl cyanide analoguesas potent EPAC antagonists

Year: 2017

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2017.04.001

Authors: Na Ye, Yingmin Zhu, Zhiqing Liu, Fang C. Mei, Haiying Chen, Pingyuan Wang, Xiaodong Cheng, Jia Zhou

Institutions: Soochow University, The University of Texas Medical Branch at Galveston, The University of Texas Health Science Center at Houston

Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: Novel Pharmacological Probes Targeting Exchange Proteins Activated by cAMP (EPAC), Epac/cAMP-GEF, A Novel Intracellular cAMP Receptor, Preclinical Development of Novel Rickettsiosis Therapeutics Targeting EPAC1

OpenAlex ID: W2604884931

FWCI: 0.76

Cites: 28

Cited by: 9

Related to: 10