CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells
Work
Year: 2017
Type: article
Abstract: Objective Cancer stem cells (CSCs) are responsible for tumour formation and spreading, and their targeting is required for tumour eradication. There are limited therapeutic options for advanced colore... more
Source: Gut
Institutions University of Rome Tor Vergata, Istituto Superiore di Sanità , Agostino Gemelli University Polyclinic, Roma Tre University, Sapienza University of Rome +3 more
Cites: 51
Cited by: 90
Related to: 10
FWCI: 4.079
Citation percentile (by year/subfield): 99.99
Subfield: Cancer Research
Domain: Life Sciences
Sustainable Development Goal Good health and well-being
Open Access status: hybrid