Year: 2017
Type: article
Abstract: From the early days of spaceflight when humans first escaped the gravitational pull of Earth, it became clear that the unloading environment of microgravity (10 −6 G) had an impact on the human skeleton. The musculoskeletal system is acutely sensitive to changes in the biomechanical environment and prolonged exposure to microgravity causes bones to demineralize, and skeletal muscles to lose mass and strength. 1 , 2 , 3 , 4 , 5 The lost tissue appears to be restored following return to normal gravity, although long-term studies have identified incomplete recovery of bone mineral density and architecture and permanent damage to bone remains a concern. 1 , 2
Source: npj Regenerative Medicine
Author: Jamie Fitzgerald
Institutions: Henry Ford Health, Henry Ford Hospital
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $4,190
OpenAlex ID: W2605163343