Work

Computational Modeling of Oxidative Stress: an Analysis of NAD(P)H Effects on Nitric Oxide and Superoxide During Hypertension

Year: 2008

Type: article

Abstract: Nitric oxide (NO) is inactivated in the human body when exposed to superoxide (02-). This reaction forms peroxynitrite (ONOO). Superoxide is produced in the cardiac system by several mechanisms, including NAD(P)H oxidase. Superoxide dismutase (SOD) breaks down superoxide into oxygen and hydrogen peroxide. This prevents superoxide from reacting with nitric oxide and allows normal function to take place. Superoxide and peroxynitrite are main contributors to vascular disease in the human body, in particular hypertension.

Source: Journal of the Arkansas Academy of Science

Author: Aaron Strobel

Language: English

Topic: Nitric Oxide and Endothelin Effects

Subfield: Physiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2605326291

FWCI:

Cites: 31

Cited by:

Related to: 10