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Scedosporium Prolificans Sclerokeratitis Following Pterygium Excision with Mitomycin C: A Case Requiring Enucleation

Year: 2017

Type: article

Abstract: Scedosporium prolificans is a rare cause of fungal sclerokeratitis following pterygium excision with beta-irradiation or Mitomycin C (MMC). We present a case of a male horticulturist with history of bilateral pterygium excision with MMC who presented for evaluation of refractory sclerokeratitis and was found to have S. prolificans sclerokeratitis. Despite aggressive topical and combination intravenous antifungal therapy, enucleation of the affected eye was required due to evidence of posterior scleral extension on imaging. S. prolificans should be considered in cases of refractory sclerokeratitis. Infections due to S. prolificans often do not respond to antifungal therapies alone and often require swift surgical management.

Source: Journal of Emerging Infectious Diseases

DOI: 10.4172/2472-4998.1000125

Authors: Nickisa M Hodgson, Helen King, Bradford W Lee, Deirdre Amaro, Don O Kikkawa, Jonathan H Lin, Bobby S Korn, Randy A Taplitz

Language: English

Topic: Ocular Infections and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2606785048

FWCI:

Cites: 9

Cited by:

Related to: 10