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An orthogonal single-molecule experiment reveals multiple-attempt dynamics of type IA topoisomerases

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Year: 2017
Type: article
Source: Nature Structural & Molecular Biology
DOI: 10.1038/nsmb.3401
Authors: Kathryn H Gunn, John F Marko, Alfonso Mondragón
Institution: Northwestern University
Language: English

Topic: Cancer therapeutics and mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: green

Funders: National Cancer Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: Spatio-Temporal Organization of Chromatin and Information Transfer in Cancer, Center for 3D Structure and Physics of the Genome, Structural and biophysical studies of DNA topoisomerases, Molecular Biophysics Training Program at Northwestern University, Activities of nucleoprotein complexes visualized in single-molecule experiments, Structural and biophysical studies of proteins, nucleic acids, and their complexes
OpenAlex ID: W2606937781
FWCI: 1.306
Cites: 32
Cited by: 28
Related to: 10
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