Work

The genetic relationship between epilepsy and hemiplegic migraine

Year: 2017

Type: review

Abstract: : Epilepsy and migraine are common diseases of the nervous system and share genetic and pathophysiological mechanisms. Familial hemiplegic migraine is an autosomal dominant disease. It is often used as a model of migraine. Four genes often contain one or more mutations in both epilepsy and hemiplegic migraine patients (ie, CACNA1A , ATP1A2 , SCN1A , and PRRT2 ). A better understanding of the shared genetics of epilepsy and hemiplegic migraine may reveal new strategic directions for research and treatment of both the disorders. Keywords: epilepsy, migraine, CACNA1A , ATP1A2 , SCN1A

Source: Neuropsychiatric Disease and Treatment

DOI: 10.2147/ndt.s132451

Authors: Yiqing Huang, Hai Xiao, Xinyue Qin, Yuan Nong, Donghua Zou, Yuan Wu

Institutions: Guangxi Medical University, Guigang City People's Hospital, First Affiliated Hospital of GuangXi Medical University, First People's Hospital of Nanning

Language: English

Topic: Migraine and Headache Studies

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,836