Work

Partial Preparation of 1-Anilino-8-(Mercaptoamino)-1,8-Octadione as a Potential Therapeutic Agent for the Treatment of Huntington’s Disease and Selected Cancers

Year: 2017

Type: article

Abstract: 1-Anilino-8-(mercaptoamino)-1,8-octadione has been identified as a compound of pharmaceutical value. The addition of carbon disulfide to sodium trimethylsilanolate to yield a xanthate product has been analyzed and refined to a 70% yield. Several methods to aminate the xanthate product to yield a sulfenamide have been attempted and analyzed. Multiple attempts have been made to benzoylate the sulfenamide product with little success, with many concerns stemming from the unsuccessful amination reactions.

Source: Digital Commons - Olivet Distinctive Heritage, Scholarship, & Creativity (Olivet Nazarene University)

Author: Macy Sprunger

Language: English

Topic: Synthesis and Reactivity of Sulfur-Containing Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2609465692

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