3P-189 Action potential frequency and energy production capability are correlated in the cerebellar neuron.(Biol & Artifi memb.:Excitation & Channels,The 47th Annual Meeting of the Biophysical Society of Japan)
Year: 2009
Type: article
Abstract: IncorporatedAssociation see3TA3-Ol 3P-182 Functionally retating mechanism of a multidrug transporter studied by coarse-grained simulation Xin-Qill Yao ( 1), Hiroo Kenzaki (1), Sheji Takada (1) ((J} kyoto Universiry, DqJariment of Bioph)･sit's.' f2) CREST, Japan Science and Teehnoiog)' (/et'pvration) induces the lateral lension in the internal monolayer, raising the probability of the hele fermation in thc membrune.Once a hole is formed, EGCg molccuTes interact with thc cdge of the hole.It reduccs its llne tension, increasing the life time of the hole, At lhe cdgc of the hole, the complcxes of EGCg and PC membranes are foimied te fold the rnembranes, eventuatty inducing the bursting.However, in the presence of cho]esterolthe life time of the hole is sma]] duc to alarge line tension, and thereby, it is difflcult for EGCg to tbrm complexes with the membranes in the ho]e.ThereforetheEGCg-inducedburstissuppressed,
Source: Seibutsu Butsuri
Authors: Takeshi Kanda, Hajime Hirase
Institutions: RIKEN Center for Brain Science, RIKEN
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W2611370641