Work

Genome-wide identification and characterization of Notch transcription complex–binding sequence-paired sites in leukemia cells

Year: 2017

Type: article

Abstract: expression. Our work provides a general method for identifying SPSs in genome-wide data sets and highlights the widespread role of NTC dimerization in Notch-transformed leukemia cells.

Source: Science Signaling

DOI: 10.1126/scisignal.aag1598

Authors: Eric Severson, Kelly L. Arnett, Hongfang Wang, Chongzhi Zang, Len Taing, Hudan Liu, Warren S. Pear, X. Shirley Liu, Stephen C. Blacklow, Jon C. Aster

Institutions: Brigham and Women's Hospital, Harvard University, Dana-Farber Cancer Institute, Dana-Farber/Harvard Cancer Center, Abramson Cancer Center, University of Pennsylvania

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Leukemia and Lymphoma Society, National Institutes of Health, National Cancer Institute

Awards: Structure and function in Notch Signaling, G3541896585, G6694682254, G7259870500, G9000084495, G9000234721

OpenAlex ID: W2611538520

FWCI: 1.666

Cites: 47

Cited by: 36

Related to: 10