Work

Stem Cell Culture and Differentiation in Microfluidic Devices Toward Organ-on-a-Chip

Year: 2017

Type: article

Abstract: and has been increasingly exploited to stem cell research. In this review, we highlight recent advances of microfluidic devices for stem cell culture and differentiation toward the development of organ-on-a-chip, especially with an emphasis on vital innovations within the last 2 years. Various aspects for improving on-chip stem-cell culture and differentiation, particularly toward organ-on-a-chip, are discussed, along with microenvironment control, surface modification, extracellular scaffolds, high throughput and stimuli. The combination of microfluidic technologies and stem cells hold great potential toward versatile systems of 'organ-on-a-chip' as desired. Adapted with permission from [1-8].

Source: Future Science OA

DOI: 10.4155/fsoa-2016-0091

Authors: Jie Zhang, Xiaofeng Wei, Rui Zeng, Feng Xu, XiuJun Li

Institutions: The University of Texas at El Paso, Xi'an Jiaotong University

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,165

Funders: National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases