Year: 2017
Type: article
Abstract: BACKGROUND: The STTR treatment cascade provides a framework for research aimed at improving the delivery of services, care and outcomes of PLWH. The development of effective approaches to increase HIV diagnoses and engage PLWH in subsequent steps of the treatment cascade could lead to earlier and sustained ART treatment resulting in viral suppression. There is an unmet need for research applying the treatment cascade to improve outcomes for those with criminal justice involvement. METHODS: The Seek, Test, Treat, and Retain (STTR) criminal justice (CJ) cohort combines data from 11 studies across the HIV treatment cascade that focused on persons involved in the criminal justice system, often but not exclusively for reasons related to substance use. The studies were conducted in a variety of CJ settings and collected information across 11 pre-selected domains: demographic characteristics, CJ involvement, HIV risk behaviors, HIV and/or Hepatitis C infections, laboratory measures of CD4 T-cell count (CD4) and HIV RNA viral load (VL), mental illness, health related quality of life (QoL), socioeconomic status, health care access, substance use, and social support. RESULTS: The STTR CJ cohort includes data on 11,070 individuals with and without HIV infection who range in age from 18 to 77 years, with a median age at baseline of 37 years. The cohort reflects racial, ethnic and gender distributions in the U.S. CJ system, and 64% of participants are African-American, 12% are Hispanic and 83% are men. Cohort members reported a wide range of HIV risk behaviors including history of injection drug use and, among those who reported on pre-incarceration sexual behaviors, the prevalence of unprotected sexual intercourse ranged across studies from 4% to 79%. Across all studies, 53% percent of the STTR CJ cohort reported recent polysubstance use. CONCLUSIONS: The STTR CJ cohort is comprised of participants from a wide range of CJ settings including jail, prison, and community supervision who report considerable diversity in their characteristics and behavioral practices. We have developed harmonized measures, where feasible, to improve the integration of these studies together to answer questions that cannot otherwise be addressed.
Authors: Redonna Chandler, Michael S. Gordon, Bridget Kruszka, Lauren N. Strand, Frederick L. Altice, Curt G. Beckwith, Mary L. Biggs, William Cunningham, J.A. Chris Delaney, Patrick M. Flynn, Carol E. Golin, Kevin Knight, Alex H. Kral, Irene Kuo, Jennifer Lorvick, Robin M. Nance, Lawrence J. Ouellet, Josiah D. Rich, Stanley Sacks, David Seal, Anne Spaulding, Sandra A. Springer, Faye Taxman, David Wohl, Jeremy D. Young, Rebekah Young, Heidi M Crane
Institutions: National Institutes of Health, National Center for Advancing Translational Sciences, Friends Research Institute, University of Washington, Yale University, Brown University, University of California, Los Angeles, Texas Christian University, University of North Carolina at Chapel Hill, RTI International, George Washington University, University of Illinois Chicago, Miriam Hospital, National Development and Research Institutes, Tulane University, Emory University, George Mason University
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,090
Funders: U.S. Department of Health and Human Services, Yale University, George Mason University, Brown University, Emory University, George Washington University, University of Washington, Tulane University, RTI International, Texas Christian University, National Institutes of Health, University of Illinois at Urbana-Champaign, University of North Carolina at Chapel Hill, National Institute of Mental Health, National Institute on Drug Abuse, National Institute of Allergy and Infectious Diseases, National Center for Advancing Translational Sciences
Awards: G1207990129, G1450643194, G2078222732, G2219438539, CARE Corrections: Technology for Jail HIV/HCV Testing, Linkage, and Care (TLC), G2852353056, Naltrexone for Opioid Dependent Released HIV+ Criminal Justice Populations, STAR-Seek, Test and Retain. Linkages for Black HIV+, Substance Using MSM, Seek, Test, Treat Strategies for Vietnamese Drug Users: A Random Controlled Trial, RCT of an augmented test, treat, link, & retain model for NC and Texas prisoners, G378552126, Abstinence Reinforcing Contingency Management to Suppress HIV Viral Load, Finding, Testing and Treating High-risk Probationers and Parolees with HIV, Seek, Test, Treat, and Retain Data Harmonization Coordinating Center, HIV Testing and Treatment to Prevent Onward HIV Transmission among High-risk MSM, G5403759994, G5859052109, A Randomized Controlled Trial and Cohort Study of HIV Testing and Linkage to Care, G6439977334, Peer-driven Intervention to Seek, Test & Treat Heterosexuals at High Risk for HIV, G711565002, Linking Russian Narcology & HIV Care to Enhance Treatment, Retention, & Outcomes, Effectiveness of Peer Navigation to Link Released HIV+ Jail Inmates to HIV Care, Improving Linkage to HIV Care Following Release from Incarceration, Planning For SUCCESS, Combination Prevention for Vulnerable Women in South Africa., Seek, Test, and Treat Strategies, Center for HIV Identification, Prevention and Treatment Services, The University of North Carolina Center for AIDS Research, Yale Clinical and Translational Science Award
OpenAlex ID: W2616221186