Year: 2017
Type: article
Abstract: Microenvironment plays important roles in leukemia initiation, progression and metastasis. While leukemia cells affect stromal cells through cell–cell contact and secreted factors, stromal cells also actively regulate leukemia cell growth and migration. 1 The extracellular matrix, which is produced and shaped by both leukemia and stromal cells, mediates the interactions between leukemia cells and their microenvironment. However, the functions of individual extracellular matrix components remain poorly understood.
Source: Leukemia
DOI: 10.1038/leu.2017.149
Institutions: Xiamen University, Putian University, Amgen (China)
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $5,190
OpenAlex ID: W2617696677