Work

Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production

Year: 2017

Type: article

Source: Cellular and Molecular Life Sciences

DOI: 10.1007/s00018-017-2541-x

Authors: Victor Tapias, Xiaoping Hu, Kelvin C. Luk, Laurie H. Sanders, Virginia M. Lee, J. Timothy Greenamyre

Institutions: Weill Cornell Medicine, University of Pittsburgh, University of Pennsylvania, VA Pittsburgh Healthcare System

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: DSF Charitable Foundation, American Parkinson Disease Association, University of Pittsburgh, National Institutes of Health, National Institute on Aging, National Institute of Neurological Disorders and Stroke, National Institute of Environmental Health Sciences

Awards: MtDNA damage as a biomarker for environmental mitochondrial toxicity, Mitochondrial Proteins in Parkinson's Disease, DJ-1 in Astrocyte-Mediated Neuroprotection Against Complex I Inhibitors, alpha-Synuclein Inhibition of Mitochondrial Protein Import, Pittsburgh Older Americans Independence Center

OpenAlex ID: W2618767189

FWCI: 8.732

Cites: 64

Cited by: 129

Related to: 10