Work

In vitro model of latent mycobacterial infection (DIV I)

Year: 2012

Type: article

Abstract: A new in vitro culture model for latency of tuberculosis pathogen suitable for screening chemical libraries was developed by subjecting the pathogen to multiple stresses that the pathogen is thought to encounter in the host. When subjected to these stress factors, the pathogen develops key features characteristic of latency, drug resistance and lipid storage. Using the culture, a method to screen chemicals was developed. This method is suitable for high through put screening.

Source: Journal of International Crisis and Risk Communication Research

Authors: Pappachan E. Kolattukudy, Jaiyanth Daniel, Chirajyoti Deb, Tatiana D. Sirakova

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2619905335

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