The Importance of Cell Signalling - Integrins and Growth Factors - in Bone Tissue Engineering: Applications for the Treatment of Osteosarcoma
Year: 2017
Type: article
Abstract: increase in parathyroid hormone and delay in bone mineralization), Paget's Disease of Bone (bone crippling disorder), osteogenesis imperfecta (OI) (stillborn infants due to fractures in utero and inability to breathe), and osteosarcoma (malignant tumor of bone). 5In this article, we provide an in-depth review of the natural bone healing process from integrins to growth factors and the repair cascade, and assess high-level biomedical applications used to treat skeletal tissue loss as the result of osteosarcoma and other disease states, as well as recent breakthroughs in the field of skeletal tissue regeneration that provide a path forward.
Author: Bill Tawil
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W2623411090